Endocrine Abstracts

Introduction: Grave’s disease (GD) is an autoimmune disease characterized by the development of thyroid-stimulating hormone (TSH) receptor antibodies that have a stimulating effect on the thyroid gland. There is a rare but non-incidental and well-documented association between GD and thymic hyperplasia (TH). Nonetheless, this association is often underdiagnosed in routine clinical practice and the mechanisms behind this association have yet to be thoroughly elucidated. Th...

Introduction: Terlipressin is a non-selective vasopressin analogue used in patients with decompensated cirrhosis, gastrointestinal haemorrhage or hepatorenal syndrome. It directly binds to V1 receptors improving circulatory volume by causing splanchnic vasoconstriction and portal hypertension inhibition, and has a full V2 receptor agonism in the collecting duct. In consequence, it increases reabsorption of water and can lead to a decrease in plasma osmolality and hyponatremia....

Purpose: To evaluate the prevalence of autonomous cortisol secretion (ACS) in patients with primary aldosteronism (PA) and its implications on cardiometabolic and surgical outcomes.Methods: A retrospective multicenter study of PA patients who underwent 1mg-dexamethasone suppression test (DST) in follow-up in 21 Spanish tertiary hospitals. ACS was defined as a cortisol post-DST >1.8μg/dL (confirmed ACS if >5μg/dL and possible ACS if between 1.8-...